• U.S. Brand Names: Pletal®
• Pharmacologic Category: Antiplatelet Agent;Phosphodiesterase Enzyme Inhibitor

• This medicine is used to relieve pain, numbness, and tingling in the legs.
• It may take 3 months to see the full effect.
• Cilostazol improves blood flow.

How to take

• Take this medicine on an empty stomach. Take 1 hour before or 2 hours after meals.

Missed Dose

• Take a missed dose as soon as possible.
• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
• Do not take a double dose or extra doses.
• Do not change dose or stop medicine. Talk with healthcare provider.

Storage

• Store at room temperature.
• Protect from light.
• Protect from moisture. Do not store in a bathroom or kitchen.

Warnings

• Do not take this medicine if you have a weakened heart.

Avoid

• If you have an allergy to cilostazol or any other part of this medicine.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
• If you have a weakened heart.
• If you are pregnant or may be pregnant.
• If you are breast-feeding.

Precautions

• If you are 65 or older, use this medicine with caution. You could have more side effects.
• If you have heart disease, talk with healthcare provider.
• If you have kidney disease, talk with healthcare provider.
• If you have liver disease, talk with healthcare provider.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• Talk with healthcare provider before using other: aspirin, aspirin-containing products, blood thinners, garlic, ginseng, ginkgo, ibuprofen or like products, pain medicines, or vitamin E.
• Tell dentists, surgeons, and other healthcare providers that you use this medicine.
• You may bleed more easily. Be careful. Avoid injury. Use soft toothbrush, electric razor.
• Avoid grapefruit and grapefruit juice.
• Avoid alcohol (includes wine, beer, and liquor).
• Use birth control that you can trust to prevent pregnancy while taking this medicine.

Side Effects

• Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.
• Headache.
• Diarrhea.

Monitoring

• Change in condition being treated. Is it better, worse, or about the same?
• Follow up with healthcare provider.

Contact a healthcare provider

• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.
• Fast heartbeat.
• Severe headache.
• Severe diarrhea.
• Severe swelling or pain of hands or feet.
• Unusual bruising or bleeding.
• Any rash.
• No improvement in condition or feeling worse.

General Statements

• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• In Canada return any unused drugs back to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th for more facts about the right way to get rid of unused drugs.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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